PHARMA AND YOUR HEALTH

PROCEDURE FOR OPERATION OF VIALS LABELING MACHINE . Procedure ·          Switch on the vials labeling machine . ·          Carry out the line clearance of the vials labeling machine and area. ·          Bring the containers of the batch to be labeled near the vials labeling machine . ·          Feed some vials in feeding hopper.

Cleaning and Disinfection of the Sterile Area after Simulation trial run studies. v   Precautions: §   Wiping of all surfaces should be done with a lint free mop. §   Mops used for wiping of area and equipment where there is media spillage should be permanently discarded after cleaning and wiping. §   All tubing used for Simulation trial run studies shall be destroyed and it should not be used for other products.

PRECAUTIONS DURING PRODUCTION ACTIVITY v   Dispensing of all the raw materials should be done in dispensing area, which should be maintained   v   Clean, dust free and hygienic to prevent contamination. Dispensed raw material should be labeled and  

 DETERMINATION OF THE FILLED VOLUME OF VIALS: v   Procedure §   Precautions: §   Use protective hand gloves. §   Ensure that the limit of fill weight/volume of the vial is given in the respective BMR.

ENTRY AND EXIT PROCEDURE: Entry procedure for Gents v   Remove the street footwear and keep in the rack provided for the same in passage in front of change room. v   Open the door and enter in to the change room. v   Remove the Ornaments like Ring, wrist watch, etc. & keep them in the locker provided. v   Cross over the bench. v   Wear the dark brown Shirt, Trouser and cap kept in the dress cabinet (for workers). v   Wear the apron and cap kept in the dress cabinet (for staff). v   Wear the foot-wear. v   Disinfect your hands with 70% IPA. v   Check in the mirror for proper attire. v   Open the door and enter in to the packing area. v   Exit procedure for Gents v   Enter in to the change room of packing area. v   Remove the footwear and keep it in the designated place below the cross over bench. v   Cross over the bench. v   Remove dark brown shirt, trouser, cap (for work...

v    Abbreviations and Definitions: ·          SOP     :            Standard Operating Procedure; a document where step by step instructions are cited to serve as support for methods or manners of fulfilling a function or functions reliably and consistently. 

Pharmaceutical process: flow chart showing processing of Raw material to form a solid Oral Dosage form All the process comprises Weighing of in-active material and Active pharmaceutical ingredient First of all raw material is dispensed as per the manufacturing plan. then the raw materials are dispensed as per the dispensing sheet, all raw materials are cross checked and re-weighed by Quality control department and manufacturing process will starts. The flow diagram also describe the manufacturing process and the process of mixing, drying,granulation, tablet punching, Milling, Coating and sugar coating and finally packing.

STERILE FILLING AND SEALING PROCESS  Sterile Dosage form are the preparations free from pyrogens and micro-organism they are injected in the body. All the sterile dosage form are pyrogen free, bacteria free and perculate matter free. There should be no visible particle in the preparations. SVP and LVP liquid and powders are formed and they are sterile products.

MANUFACTURING OF PURIFIED WATER AND WATER FOR INJECTION Water for injection and purified water are prepared or processed . Formulation of water for injection from simple water is done by treating it with some method or process. First of all water is transferred from the multi-media filter and collected, then it is transferred to to another filter connected to it. Now water is transferred to Carbon filter which is further connected to to water softener.

GRANULATION PROCESS: Granulation process :-  It is a process in which the  powder particles are made to adhere to form larger, multi particle entities called granules.  A dough mass is prepared to form the granules.

1938: Di-ethyl stilbestrol (DES) was created. DES was the first synthetic estrogen ever synthesized; it was cheap to produce, more potent than natural estrogen, and could be taken orally. In the rush to make and market DES, Eli Lilly became one ofthe drug's major manufacturers. In America alone there were 267 drug companies that made and distributed DES and other similar synthetic estrogen because it was un-patented and easily produced.No controlled studies were ever conducted by the drug companies to determine the effectiveness or safety of DES for use during pregnancy, even after some scientists started questioning its efficacy in the 19505. As early as 1953, research revealed that DES did not work that DES actually brought about higher rates of premature birth and infant mortality yet DES continued to be prescribed to pregnant women for decades. 

It is often seen and heard about pharmaceutical giants or industry as a whole having a constant GDP, employment being unaffected by famine, war, or any other catastrophes. In a sense they are humanities lifeline and that to with secure employment and good stock options! If anything can compare to it, then the nearest would be oil!

 Benefits of Allopathy : Allopathic medicine excels when treating acute and life-threatening illness and injuries. Modern medical imaging technologies, surgical procedures, and doctors diagnose and treat us when we are very ill and injured. Many lives have been saved, and quality of life returned, thanks to highly skilled doctors and modern medical technologies.

Digital pill  What is it?  It is a device, made by Proteus Digital Health. It is a silicon chip about the size of a sand particle. With no battery and no sensor, it is powered by the body itself.