Skip to main content

STERILE FILLING AND SEALING

STERILE FILLING AND SEALING PROCESS


 Sterile Dosage form are the preparations free from pyrogens and micro-organism they are injected in the body. All the sterile dosage form are pyrogen free, bacteria free and perculate matter free. There should be no visible particle in the preparations.

SVP and LVP liquid and powders are formed and they are sterile products.





Filling and sealing of Ampules in a approved sterile filling area .All filling and sealing process is carried out by trained or approved workers in Approved manufacturing industry.
Approval of manufacturing area is given by local or inter National Authorities.

After filling and sealing the ampules and vials are kept under sterilization process in Autoclave.
After sterilization ampules or vials are visually checked by trained workers and then they are sent to the packaging department, where they are packed by automated or semi-automated machines .
In some industries they are also packed by hand packing.

Comments

Popular posts from this blog

CINNAMON AS ANTI MICROBIAL AGENT

Hands are primary mode of transmission of microbes and infections. Through hand hygiene a simple and least expensive means of prevent health care associated infections specially derived from environmental surfaces. The present research was aimed to evaluate the antimicrobial efficacy of Cinnamon oil extract found that it showed better antimicrobial activity. Also the research was carried out to formulate and evaluate the Hand wash gel containing Cinnamon oil. The anti-microbial activity of the formulated hand wash gel was tested against Escherichia coli, Staphylococcus aureus, Bacilius subtilis and pseudomonas vulagaris by spread plate techniques and the results obtained were compared with standard antibiotic.

DNA FINGERPRINTING

Medicinal plants have been used universally since ancient days to sustain health and to treat diseases. However, adulteration and use of specious materials as substitutes have become a major apprehension for users and industry for reasons of safety and efficacy. Therefore, authentication of medicinal plants is of utmost importance. Morphological, anatomical, chemical and DNA markers solve the problem by differentiating the genuine material from the adulterants, substitutes and spurious drugs. 

GRANULATION PROCESS

GRANULATION PROCESS: Granulation process :-  It is a process in which the  powder particles are made to adhere to form larger, multi particle entities called granules.  A dough mass is prepared to form the granules.