INVITRO EVALUATION OF ANTIOXIDANT PROPERTIES OF COMMICARPUS CHINESIS

The present investigation deals with the extraction of roots of Commicarpus chinensis, preliminary phytochemical screening and evaluation of antioxidant activity using various in-vitro methods. The roots were subjected to extraction by soxhelation for ether and ethanol. The water extracts was obtained from maceration process.

The extracts were subjected to evaluation for antioxidant activity by DPPH free radical scavenging method, nitric oxide radical scavenging method and reducing power determination. The extracts obtained were subjected to preliminary phytochemical screening for detection of chemical constituents present in them. The preliminary phytochemical screening of crude extract revealed the presence of carbohydrates, amino acids, steroids, glycosides, saponin, tannins & phenolic compounds and flavonoids.

The in~vitro antioxidant activity of extracts was determine by DPPH, nitric oxide (NO) activity and reducing power assay the ethanol and water extracts shows significant results.

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GRANULATION PROCESS

GRANULATION PROCESS: Granulation process :- It is a process in which the powder particles are made to adhere to form larger, multi particle entities called granules. A dough mass is prepared to form the granules.

CINNAMON AS ANTI MICROBIAL AGENT

Hands are primary mode of transmission of microbes and infections. Through hand hygiene a simple and least expensive means of prevent health care associated infections specially derived from environmental surfaces. The present research was aimed to evaluate the antimicrobial efficacy of Cinnamon oil extract found that it showed better antimicrobial activity. Also the research was carried out to formulate and evaluate the Hand wash gel containing Cinnamon oil. The anti-microbial activity of the formulated hand wash gel was tested against Escherichia coli, Staphylococcus aureus, Bacilius subtilis and pseudomonas vulagaris by spread plate techniques and the results obtained were compared with standard antibiotic.

WONDER DRUG FAKE OR REALITY ?

1938: Di-ethyl stilbestrol (DES) was created. DES was the first synthetic estrogen ever synthesized; it was cheap to produce, more potent than natural estrogen, and could be taken orally. In the rush to make and market DES, Eli Lilly became one ofthe drug's major manufacturers. In America alone there were 267 drug companies that made and distributed DES and other similar synthetic estrogen because it was un-patented and easily produced.No controlled studies were ever conducted by the drug companies to determine the effectiveness or safety of DES for use during pregnancy, even after some scientists started questioning its efficacy in the 19505. As early as 1953, research revealed that DES did not work that DES actually brought about higher rates of premature birth and infant mortality yet DES continued to be prescribed to pregnant women for decades.

PHARMA AND YOUR HEALTH

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