Skip to main content

RECENT ADVANCES IN NOVEL DRUG DELIVERY SYSTEMS

Drug delivered can have significant effect on its efficacy. Some drugs have an optimum concentration range with in which maximum benefit is derived and concentrations above (or) below the range can be toxic or produce no therapeutic effect. Various drug delivery and drug targeting systems are
currently under development. The aim goal for developing such delivery systems is to minimize drug 
degradation and loss, to prevent harmful side effects and to increase bio availability.




Targeting is the ability to direct the drug loaded system to the site of interest. Among drug carrier one can name soluble polymers, microparticles made of insoluble (or) biodegradable natural and synthetic polymers. Two major mechanisms can be distinguished for addressing the desired sites for drug release, (a) Passive and (b) Active targeting.

Controlled drug carrier systems such as micellar solutions, vescicles and liquid crystal dispersions, as
well as nanoparticle dispersions consisting of small particles of 10 – 400 nm show great promise as drug delivery systems. Hydrogels are three dimensional, hydrophilic, polymer networks capable of imbibing large amounts of water or biological fluids. Buckyballs, a novel delivery system with 60 carbon atoms formed in the shape of hollow ball. 

They are other type’s namely bucky babies, fuzzy balls, gadofullereness, and giant fullerenes. Nanoparticles can be classified as nano tubes, nano wires, nano cantilever, nanoshells, quantum dots, nano pores. Researchers at north western university using gold particles to develop ultra sensitive detection systems for DNA and protein markers associated with many forms of cancer, including breast and prostrate cancer. Drug loaded erythrocytes is one of the growing and potential systems for delivery of drugs and enzymes

Comments

Post a Comment

Popular posts from this blog

CINNAMON AS ANTI MICROBIAL AGENT

Hands are primary mode of transmission of microbes and infections. Through hand hygiene a simple and least expensive means of prevent health care associated infections specially derived from environmental surfaces. The present research was aimed to evaluate the antimicrobial efficacy of Cinnamon oil extract found that it showed better antimicrobial activity. Also the research was carried out to formulate and evaluate the Hand wash gel containing Cinnamon oil. The anti-microbial activity of the formulated hand wash gel was tested against Escherichia coli, Staphylococcus aureus, Bacilius subtilis and pseudomonas vulagaris by spread plate techniques and the results obtained were compared with standard antibiotic.
Post a Comment
Read more

DNA FINGERPRINTING

Medicinal plants have been used universally since ancient days to sustain health and to treat diseases. However, adulteration and use of specious materials as substitutes have become a major apprehension for users and industry for reasons of safety and efficacy. Therefore, authentication of medicinal plants is of utmost importance. Morphological, anatomical, chemical and DNA markers solve the problem by differentiating the genuine material from the adulterants, substitutes and spurious drugs. 
Post a Comment
Read more

GRANULATION PROCESS

GRANULATION PROCESS: Granulation process :-  It is a process in which the  powder particles are made to adhere to form larger, multi particle entities called granules.  A dough mass is prepared to form the granules.
Post a Comment
Read more