JAATYADI GHRITA : AS POTENT WOULD HEALING AGENT IN DIABETIC ANIMAL MODEL

Diabetes is a disease of altered glucose homeostasis and persistent hyperglycemia lead to advanced glycation end product (AG E) which are primarily responsible for the damage of cells which have a slow turn over (like neuronal tissue).This abnormality results in poor wound healing. Further hyperglycemic complication leads to wound infection. Wound management is a significant and growing health burden on the community. In the Indian context, the formal descriptions of wound care have been vividly elaborated in the three great treatises (Brahatrayi) of Ayurveda viz. Charaka Samhita.

Sushruta Samhita and Astanga Sangraha. Some of the herbal drugs with proven antidibetic and wound healing activity are Jaati (Jasminum 0fficinale linn). Neem (Azadirachta indica AJuss),Patol (Trichiosanthes dioica. Roxb),Haridra (Curcuma longs linn.) The present work is aimed to standardize and to evaluate the diabetic wound healing activity of poly herbal formulation, JAATYADI GHRITA containing these herbs. The work also includes Evaluation of Physicochemical Parameters, Phytochemical screening, Quantitative estimation of identified phytoconstituents using HPTLC & HPLC analysis and in~vitro antimicrobial studies. This will act as a referential source of infomtation for researchers who have interest in the relevant field.

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